Tosifusa Toda, Ph.D.

Address: 2-5-14 Uenohara, Higashikurume, Tokyo 203-0001, Japan.

Home Tel. No.: +81-3-42-475-1544

Nationality: Japanese

Birthday and birthplace: July 23, 1951, Fukui Prefecture

Current Affiliation

  Proteomic Gerontology Research Unit, Leader

  Research Team for Molecular Biomarkers,

  Tokyo Metropolitan Institute of Gerontology

  (Concurrent: TMIG Proteomics Collaboration Center, Head)

  35-2 Sakaecho, Itabashiku, Tokyo 173-0015, Japan

  Tel: +81-3-3964-3241 (Ex. 3182)

  Fax: +81-3-3579-4776

  Email: toda2d@tmig.or.jp

Educational Background

1967-1970 Fujishima Senior High School; Completed,

1971-1975 Osaka University, School of Science, Undergraduate Course of Chemistry; Graduated,

1975-1977 Osaka University, Graduate School of Science, Department of Biology; Completed the Master course  receiving the degree of Master of Science,

1988 Received the Ph.D. from Osaka University on the dissertation entitled “Purification and identification of intermediate catabolic products in the in vitro degradation”

Awards

1983 The 22nd Kodama Memorial Award from the Japanese Electrophoresis Society

2005 The 2nd International Exchange Promoting Award from the Japanese Electrophoresis Society

Work Experiences

1977-1988  Tokyo Metropolitan Institute of Gerontology, Laboratory of Biochemical Research, Assistant Researcher

1988-1989  University of California, San Francisco, Laboratory of Dermatology Research, Visiting Research Scientist

1988-2002  Tokyo Metropolitan Institute of Gerontology, Laboratory of Molecular Biology, Senior Research Scientist

2002-2005  Tokyo Metropolitan Institute of Gerontology, Collaborative Research Group for Proteomics, Group Leader

2005-present  Tokyo Metropolitan Institute of Gerontology, Research Team for Molecular Biomarkers, Proteomic Gerontology Research Unit, Leader

Concurrent: TMIG Proteomics Collaboration Center, Head)

Affiliations to Academic Societies

Japanese Electrophoresis Society, Vice-president

Japan Human Proteome Organization, Council Member

Japan Society for Biomedical Gerontology, Council Member

Japanese Biochemical Society, Member

Molecular Biology Society of Japan, Member

Japanese Cancer Association, Member

Japanese Society of Clinical Chemistry, Member

Latest Major Works

"Proteomic analysis of Epstein-Barr virus-transformed human B-lymphoblastoid cell lines before and after immortalization"

Toda, T., Sugimoto, M., Omori, A., Matsuzaki, T., Furuichi, Y., Kimura, N. (2000) Electrophoresis, 21 (9), 1814-1822.


"An extra human chromosome 21 reduces mlc-2a expression in chimeric mice and Down syndrome"

Nishigaki R, Shinohara T, Toda T, Omori A, Ichinose S, Itoh M, Shirayoshi Y, Kurimasa A, Oshimura M. (2002) Biochem Biophys Res Commun. 295(1), 112-118.

"Proteomic approach to determination of the significance of protein oxidation in the ageing of mouse hippocampus"

Toda, T., Morimasa, T., Kobayashi, S., Nomura, K., Hatozaki T., and Hirota, M. (2003) Appl Genomics Proteomics 2(1), 43-50


"Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene"

Hiratsuka M, Inoue T, Toda T, Kimura N, Shirayoshi Y, Kamitani H, Watanabe T, Ohama E, Tahimic CG, Kurimasa A, Oshimura M. (2003) Biochem Biophys Res Commun. 309(3), 558-566.


"Citrullination preferentially proceeds in glomerular Bowman's capsule and increases in obstructive nephropathy."

Feng D, Imasawa T, Nagano T, Kikkawa M, Takayanagi K, Ohsawa T, Akiyama K, Ishigami A, Toda T, Mitarai T, Machida T, Maruyama N. (2005) Kidney Int, 68, 84-95.


"Proteomic identification of differentially-expressed genes in human gastric carcinomas."

Nishigaki R, Osaki M, Hiratsuka M, Toda T, Murakami K, Jeang KT, Ito H, Inoue T, Oshimura M. (2005) Proteomics, 5, 3205-3213.


"Collaborative proteomics framework with XML databases and an integrated XML viewer for 2DPAGE."

Morisawa H, Toda T. (2005) J Electrophoresis, 49(1), 35-38.


"Age-dependent variations of cell response to oxidative stress: proteomic approach to protein expression and phosphorylation."

Miura Y, Kano M, Abe K, Urano S, Suzuki S, Toda T. (2005) Electrophoresis, 26(14), 2786-2796.


"Comparative proteomics of flotillin-rich Triton X-100-insoluble lipid raft fractions of mitochondria and synaptosome from mouse brain."

Nakamura M, Sakurai Y, Takeda Y, Toda T., (2005) J Electrophoresis, 49(4), 77-83.


"Proteomic Study on the variation of protein expression and phosphorylation caused by radiation in culture grial cells. "

Miura Y. Kano M, Toda T, Suzuki S. (2005) Biol Sci Space, 19(2), 98-99.

For further information, visit the web site of PROTEOMICSRESEARCH.ORG.